Top 5 Coins to Buy and Hold Long-Term Amid Trump’s Big Bet on Crypto

The renewed political spotlight on cryptocurrency under Donald Trump’s pro-crypto agenda has ignited fresh optimism across the digital asset market. With promises of making the U.S. the global crypto capital, investors are now prioritizing tokens with long-term utility, strong development pipelines, and explosive upside potential. Little Pepe ($LILPEPE) is at the top of the list of standout options that are getting a lot of attention. Analysts say it is the best buy token for investors preparing for the next big crypto cycle. Along with Little Pepe, tokens like Sei, Arbitrum, Hedera, and Ethena are all becoming strategic long-term picks. They all possess strong fundamentals and a clear role in a pro-blockchain legislative environment.

Little Pepe (LILPEPE)

Little Pepe is dominating market attention as one of the fastest-selling presales of 2025. Now, in Stage 13 at just $0.0022, the token has already doubled the profits of early investors and raised over $27 million, signaling extraordinary long-term demand. Analysts describe it as the number one cryptocurrency to buy and hold due to its blend of meme culture, technology, and real-world ecosystem utility. Unlike traditional meme coins, Little Pepe is building the world’s first Layer-2 blockchain designed exclusively for meme tokens, offering ultra-fast speeds, extremely low fees, and a built-in meme launchpad for instant token creation. This gives it real infrastructure utility, something meme coins like SHIB and PEPE never had at launch. With planned listings on two tier-one centralized exchanges and a potential listing on one of the globe’s biggest exchanges, Little Pepe is positioned to skyrocket once it hits the open market. Analysts project 100× to 500× potential, with a real chance of becoming the next billion-dollar meme ecosystem.

Sei (SEI)

Sei remains one of the fastest Layer-1 networks in the cryptocurrency industry, even at $0.16. It offers the best transaction finality, making it ideal for high-performance trading apps. It is a solid long-term investment, as it can grow, has a structure that makes it easier to sell, and the DeFi ecosystem is constantly evolving. As the Trump administration makes the rules and structures for businesses and governments clearer, businesses and trade protocols are likely to use blockchains like Sei, which focus on speed and efficiency.

Arbitrum (ARB)

At $0.24, Arbitrum is still the greatest Layer-2 network for Ethereum transactions that can grow. It runs thousands of decentralized apps and has billions of dollars in locked liquidity. If the Trump administration continues to push for increased blockchain adoption and clearer regulations, Ethereum scaling networks are likely to benefit significantly. Arbitrum's long-term stability is demonstrated by its well-integrated nature within the Ethereum ecosystem, with numerous developers actively working on it, and the presence of recurring ecosystem grants. Analysts think that when demand for Ethereum goes up during the next expansion cycle, the price will go back to the $2.50–$4.00 area.

Hedera (HBAR)

At $0.15, Hedera is one of the few blockchain-like networks with genuine institutional backing. With governing council members including IBM, Google, Boeing, and LG, Hedera is positioned as a trusted enterprise solution for asset tokenization, identity, and real-time payment systems. With a U.S. administration vocally committed to strengthening blockchain infrastructure and digital asset innovation, Hedera may benefit more than most from future corporate integrations and public-sector applications. HBAR could realistically climb back into the $0.30–$0.50 range as adoption accelerates.

Ethena (ENA)

At $0.44, Ethena has quickly built one of the most disruptive models in crypto through its synthetic dollar and sustainable on-chain yield systems. In a market where institutional inflows may rise, protocols offering stable yield could become some of the most utilized. ENA’s expanding ecosystem, rising liquidity, and integration across major exchanges make it a strong contender for long-term accumulation. Ethena may revisit the $1.50–$2.00 territory in a favorable macro environment.

Conclusion

While Sei, Arbitrum, Hedera, and Ethena each provide strong long-term fundamentals, Little Pepe ($LILPEPE) stands out as the asset with the highest upside, thanks to its explosive presale momentum, massive community energy, and first-of-its-kind Layer 2 meme ecosystem. As Trump’s agenda pushes crypto deeper into mainstream adoption, tokens with strong narratives and scalable utility are set to thrive. For investors seeking both long-term growth and high multipliers, Little Pepe remains the clear leader among the top 5 coins to buy and hold.

For more information about Little Pepe (LILPEPE) visit the links below:

Website: https://littlepepe.com

Whitepaper: https://littlepepe.com/whitepaper.pdf

Telegram: https://t.me/littlepepetoken

Twitter/X: https://x.com/littlepepetoken

$777k Giveaway: https://littlepepe.com/777k-giveaway/