Gintama : Insane and unpredictable comedy with an encapsulating blend of sci-fi, action, and satire that no other anime comes near to.
One Punch Man : Far too powerful a hero for his good, One Punch Man perfectly satirizes the superhero tropes using brilliant writing and brilliant timing.
Grand Blue : There is College, there is booze, and absurd humor. Grand Blue is just chaos and laughter all over an episode.
The Disastrous Life of Saiki K : Having psychic powers sounds cool-unless you're Saiki. This deadpan comedy is a cult favorite for a reason.
KonoSuba : KonoSuba shamelessly jams in jokes as it parodies the isekai genre, featuring lovable (and ridiculous) characters.
Nichijou : Every day, school life becomes a lot of surreal comedy gold. It's random, it's witty, and it's gorgeously animated.
Hinamatsuri : Conceived with a mix of awkwardness: A turn-of-the-century yakuza meets a telekinetic girl in a heartwarming way.
Monthly Girls’ Nozaki-kun : A teen in love with her crush, who is nothing but an oblivious shoujo manga artist. Sweet and side-splitting.
Prison School : Extremely and unforgivably outrageous, this is comedy in its purest, unfiltered, absurd-N.S.F.W. formula.